Structure and Functions of the Human Gas Exchange System
Senior 1 · Biology
Structure and Functions of the Human Gas Exchange System
Lesson 2 of 5
25 min
A moto passes you on a murram road in the dry season and leaves a cloud of red dust. You cough, and later the mucus you blow from your nose is brown. Yet the air that reaches your alveoli, deep in the lungs, is almost free of dust, warm and moist, whatever the weather outside. Something on the way cleaned, warmed and wetted it.
In Lesson 1 you named the parts of the gas exchange system. In this lesson you will see that each part has a structure that suits its job. Biologists call this the link between structure and function.
A. On your own neck. Rest two fingertips lightly on the front of your neck, just below the bump of the larynx (the "Adam's apple"). Move them slowly downwards: you can feel firm ridges, the rings of cartilage of the trachea. Keep your fingers on the larynx and swallow: the larynx moves up. As it rises, a flap called the epiglottis closes over it, so that food and drink go down the oesophagus and not into the trachea.
B. Under the microscope. Look at a prepared slide of lung tissue, first with the low-power objective () and then with the high-power objective (). Find one tube with a thick, folded lining: a bronchiole. Around it, find many empty spaces separated by very thin walls: the alveoli.
Safety. Press gently on your own neck only, never on another person's. Carry the microscope with two hands, and focus with the coarse focus only at low power, as you learned in Unit 4.
Definition
Cartilage: a firm but flexible tissue, softer than bone. Example: the rings of the trachea, and the tip of your nose.
Epiglottis: a flap of cartilage above the larynx that closes over it when you swallow.
Mucus: a sticky liquid made by goblet cells in the lining of the airways. It traps dust and bacteria.
Cilia: tiny hair-like structures on the ciliated cells that line the airways. They beat together, sweeping mucus upwards to the throat. You met ciliated cells in Unit 6.
Surface area: the total area of a surface, measured in square metres, . Example: a floor 3 m by 4 m has a surface area of .
Table 1: The parts of the gas exchange system and how each is built for its job
| Part | Structure | How the structure fits the function |
|---|---|---|
| Nasal cavity | hairs; a lining that makes mucus and carries cilia; many small blood vessels | Hairs and mucus trap dust and bacteria. The warm, moist lining warms the air and adds water vapour, so cold, dry air does not damage the lungs. |
| Pharynx | a muscular tube shared by air and food, with the epiglottis above the larynx | When you swallow, the epiglottis covers the larynx, so food goes into the oesophagus, not the trachea. |
| Larynx | a box of cartilage containing the vocal cords | The cartilage keeps the airway open. Air passing out over the vocal cords makes them vibrate: this is your voice. |
| Trachea | C-shaped rings of cartilage; a lining of ciliated cells and mucus-making goblet cells | The rings stop the trachea collapsing when the air pressure inside it falls as you breathe in. Mucus traps dust and bacteria; cilia sweep the mucus up to the pharynx, where it is swallowed. |
| Bronchi | like the trachea: cartilage, cilia and mucus | Carry air into each lung and stay open, while the lining goes on cleaning the air. |
| Bronchioles | narrow tubes with no cartilage; smooth muscle and elastic fibres in the wall; branch many times | Branching carries air to every part of the lung. The muscle can widen or narrow the bronchioles, changing how easily air flows (Lesson 5). |
| Alveoli | about 300 million in each lung; walls one cell thick; a moist lining; a dense net of capillaries | A huge surface area, a very short distance for diffusion, a wet surface for gases to dissolve in, and blood that is always carrying away and bringing : all make gas exchange fast. |
| Pleural membranes | two smooth membranes with fluid between them | The fluid lets the lungs slide against the chest wall with almost no friction as you breathe. |
| Ribs and intercostal muscles | a cage of bone, with muscles between the ribs | Protect the heart and lungs; the muscles move the ribs to change the volume of the thorax (Lesson 3). |
| Diaphragm | a dome-shaped sheet of muscle | Contracts and flattens to make the thorax bigger (Lesson 3). |
Figure 1 shows the trachea cut across. The cartilage is not a complete circle: it is a letter C, open at the back, where the trachea lies against the oesophagus.
Figure 1: The trachea cut across, with the front of the neck at the top.
The C shape does two jobs at once. The stiff front and sides stop the airway being squashed flat when you breathe in hard. The soft gap at the back lets the oesophagus bulge forward when a mouthful of food passes down it.

Gas exchange is fast when four things are true, and the alveoli have all four:

Warning
Three common mistakes
Worked example 1: how big is 75 square metres?
The alveoli of an adult have a total surface area of about . A volleyball court measures 18 m by 9 m. What fraction of the court could the alveoli cover?
Why it matters: a surface this large, packed into a space the size of your chest, is what lets enough enter the blood with every breath.
Worked example 2: reading a micrograph
Look at the photo of lung tissue above. Identify the bronchiole and the alveoli, and give two differences between them.
Link: the thin walls are the reason the alveoli, and not the bronchioles, exchange gases.
In Rwanda's dry seasons, unpaved roads, building sites and brick-making sites send fine dust into the air. Most of the dust you breathe in is caught by the hairs and mucus in your nose, or by the mucus in your trachea and bronchi, and the cilia carry it up to your throat to be swallowed or coughed out. That is why mucus looks darker after a dusty journey.
Three habits help this cleaning system: breathe through your nose rather than your mouth; sprinkle the classroom floor with water before sweeping, so the dust stays down; and wear a dust mask for dusty work such as sanding, quarrying or brick-making.
Freesciencelessons: "Gas Exchange in the Lungs". As you watch, list the features of the alveoli that the video names, and match each one to the Alveoli row of Table 1.
Tip
Memory hook for the alveoli: "big, thin, wet and well fed". Big surface area, thin walls, a wet lining, and well fed by a rich blood supply. In an exam, give the feature and say how it helps: "The wall is one cell thick, so the diffusion distance is short."
Practice: structure and function
Key points
Sources and credits
Table 1, Figure 1, the observation activity, the worked examples and the practice questions are written by Ganzaa.
This lesson adapts CC BY-SA material and is shared under CC BY-SA 4.0.